The Saxon Network for Radionuclide Theranostics (SNRT) is dedicated to the development, production and application of radionuclide-labeled drugs (radiopharmaceuticals) for the European market. As a research partner, the VKTA is responsible for the radiological evaluation of nuclides for diagnostic and therapeutic purposes as well as production-related impurities and the management of their disposal in strict compliance with radiation protection regulations.
We use both measuring and calculation methods (e.g. nuclide kinetics, burn-up and shielding, radioecological modeling) to determine relevant source terms (nuclide vectors) and dose quantities, using both established and in-house developed software solutions.
Förderkennzeichen: 03RU3U041C
Contact:
Dr. Willy Ciecior
Sven Jansen
Dr. Henry Lösch
Figure. Exemplary output of an in-house software solution for the time-dependent determination of nuclide vectors, taking the respective clearance value according to Annex 4 of the Radiation Protection Ordinance and the efficiency (calibration factor) of a measuring device (here for surface contamination) into account. As output, a time-dependent clearance score integrating information both about the radiological relevance as well as the efficiency of a measuring device and the correspondingly most unfavorable time point of a clearance (here 199 days after initiation) is received. Furthermore, time-dependent monitor units of the measuring device per becquerel are presented. Calculations are possible for nuclide vectors of any complexity both analytically (fast) and numerically (with high precision) and serve to support decision-making processes in clearance procedures.